| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | AAK1 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 20 µL |
|---|
| Concentration | n/a |
|---|
| Applications | Western Blot: 1:1,000 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | AAK1 Polyclonal Antibody. AP2-associated protein kinase 1 (Aak1) is a member of the Ark1/Prk1 subfamily of Ser/Thr protein kinases that are thought to regulate endocytosis by phosphorylating the accessory endocytic components. Aak1 interacts with and phosphorylates the mu2 subunit of the AP-2 complex, which promotes binding of the AP-2 to tyrosine based (Yxxphi) internalization motif-containing receptors and subsequent receptor endocytosis. At least two isoforms of Aak1 are known to exist; the longer isoform contains an extended carboxy-terminus that contains an additional clathrin-binding domain. Overexpression of this long isoform or Aak1 depletion by RNA interference impairs transferrin recycling from the early/sorting endosome, suggesti |
|---|
| Immunogen | n/a |
|---|
| Other Names | AP2-associated protein kinase 1; Adaptor-associated kinase 1; AAK1; KIAA1048 |
|---|
| Gene, Accession # | Entrez: 22848; Uniprot: Q2M2I8 |
|---|
| Catalog # | A302-146A-T |
|---|
| Price | |
|---|
| Order / More Info | AAK1 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|