| 产品详情 |
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| Product Name | A-66 |
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| Description | Purity >98%. A-66 is a potent, selective inhibitor of the PI3K isoform p110Alpha (IC50 = 32 nM in a cell-free assay). It displays over 100-fold selectivity for p110Alpha over other isoforms. A-66 is effective in vivo, suppressing the growth of SK-OV-3 tumor xenografts in mice. It also impairs all measures of in vivo insulin action in mice. A-66 partially suppresses B cell receptor-dependent Akt activation and proliferation. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (2S)-N1 -[2-(1,1-dimethylethyl)-4'-methyl[4,5'-bithiazol]-2'-yl]-1,2-pyrrolidinedicarboxamide |
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| Gene, Accession, CAS # | CAS: 1166227-08-2 |
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| Catalog # | LS-H6357 |
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| Price | |
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| Order / More Info | A-66 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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