| 产品详情 |
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| Product Name | 17-AAG |
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| Description | Purity >98% by HPLC. A semi-synthetic derivative of Geldanamycin that displays greater stability and lower in vivo toxicity compared to Geldanamycin. Binds to Heat shock protein 90 (Hsp90) (EC50 = 7.2 µM) in a manner similar to geldanamycin. Exhibits 100-fold higher affinity for tumor-derived Hsp90 over normal cells. Also inhibits Akt activation and HER2 expression in tumor cells. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Tanespimycin, 17-(Allylamino)geldanamycin, 17-(Allylamino)-17-demethoxygeldanamycin, NSC330507 |
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| Gene, Accession, CAS # | CAS: 75747-14-7 |
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| Catalog # | LS-H2472 |
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| Order / More Info | 17-AAG from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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