产品详情 |
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Antigenic Specificity | TL1A/TNFSF15 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 100ug (sample available) |
Concentration | 0.5-1mg/ml, actual concentration varies by lot. |
Applications | ELISA, IHC, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit IgG polyclonal Picoband™ antibody for TL1A detection. Tested with WB, IHC-P, ELISA(Cap) in Human;Mouse;Rat. No cross reactivity with other proteins. Vascular endothelial growth inhibitor (VEGI), also known as TNF-like ligand 1A (TL1A) and TNF superfamily member 15 (TNFSF15), is protein that in humans is encoded by the TNFSF15 gene. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene. |
Immunogen | E. coli-derived human TL1A recombinant protein (Position: L72-T244). |
Other Names | Tumor necrosis factor ligand superfamily member 15; TNF ligand-related molecule 1; Vascular endothelial cell growth inhibitor; Tumor necrosis factor ligand superfamily member 15; membrane form; Tumor necrosis factor ligand superfamily member 15; secreted form; TNFSF15; TL1; VEGI |
Gene, Accession # | TNFSF15, UniProt: O95150 |
Catalog # | A02402-1 |
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Order / More Info | TL1A/TNFSF15 Antibody from BOSTER BIO |
Product Specific References | n/a |
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