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| Product Name | A 410099.1 |
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| Description | High affinity XIAP antagonist (Kd = 16 nM for the BIR3 domain of XIAP). Exhibits cytotoxicity in a wide range of cancer cell lines in vitro (EC50 = 13 nM in MDA-MB-231 cells). Also displays antitumor activity in a mouse breast cancer xenograft model. Enhances TRAIL-induced apoptosis in chronic lymphocytic leukemia (CLL) cells. Purity 98%. MW (observed): 505.09 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-Methyl-L-alanyl-(2S)-2-cyclohexylglycyl-N-[(1R)-1,2,3,4-tetrahydro-1-naphthalenyl]-L-prolinamide hydrochloride |
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| Gene, Accession, CAS # | CAS: 762274-58-8 |
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| Catalog # | 6470/10 |
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| Price | |
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| Order / More Info | A 410099.1 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 19920200 |
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