| 产品详情 |
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| Product Name | BIX-01294 |
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| Description | BIX-01294, a diazepin-quinazolinamine derivative, is a selective,cell-permeable G9a-like protein and G9a histone lysine methyltransferase (HMTase) inhibitor (IC50 values are 0.7 and 1.7 uM respectively) that displays little or no activity at other HMTases. BIX-01294 has been used in combination with the calcium channel activator BayK8644 to facilitate the generation of induced pluripotent stem cells from somatic cells in vitro. BIX-01294 and valproic acid, a histone deacetylase (HDAC) inhibitor, may replace the requirement for ectopic OCT4 (POU5F1) and cMyc respectively in pluripotent stem cell induction (iPS) recipes. |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | Activator or Inhibitor |
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| Other Names | HMT inhibitor |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | P018-5MG |
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| Order / More Info | BIX-01294 from ARBOR ASSAYS, INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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