| 产品详情 |
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| Antigenic Specificity | Synaptophysin 1 |
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| Clone | 7.2 |
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| Host Species | Mouse |
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| Reactive Species | human, rat, mouse |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | IHC, Paraffin Sections (FFPE), Western Blot, Immunoprecipitation, Immunocytochemistry, ELISA |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Useful Marker for normal neuroendocrine cells and neuroendocrine tumors: Synaptophysin is a most reliable and specific marker molecule for normal and neoplastic neuroendocrine cells in the nerveous system. Synaptophysin 1 is a membrane glycoprotein of synaptic vesicles that is ubiquitously expressed in all neurons and in many endocrine cells. It forms a complex with dynamin at high Ca2+ concentration suggesting an involvement in synaptic vesicle endocytosis. |
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| Immunogen | Electrophoretically purified synaptophysin. Epitope: Reacts with cytoplasmic tail of synaptophysin 1, no cross-reactivity to other synaptophysins. |
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| Other Names | major synaptic vesicle protein p38, MRXSYP, Syn, p38, AI848995, A230093K24Rik, Syp1, mrxsyp, syp, xsypi, syp-B, xsypii, MGC86267 |
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| Gene, Accession # | SYP, 6855 |
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| Catalog # | SySy101011 |
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| Price | |
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| Order / More Info | Synaptophysin 1 Antibody from DIANOVA GmbH |
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| Product Specific References | The expression pattern and assembly profile of synaptic membrane proteins in ribbon synapses of the developing mouse retina. von Kriegstein K & Schmitz F. Cell Tissue Research 311: 159-73, 2003. / Distribution of synaptic vesicle proteins in the mammalian retina identifies obligatory and facultative components of ribbon synapses. von Kriegstein K, Schmitz F, Link E & Sudhof T. European Journal of Neuroscience 11: 1335-48, 1999 |
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