| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Phospho-SMAD2 (Ser245, Ser250, Ser255) |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 100 µL |
|---|
| Concentration | n/a |
|---|
| Applications | Western Blot: 1:500-1:3000 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Phospho-SMAD2 (Ser245, Ser250, Ser255) Polyclonal Antibody. SMAD2 (MADH2, MAD2) regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. SMAD2 interacts with the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation into the nucleus is a central event in TGF beta signaling. Phosphorylation of threonine 8 in the calmodulin-binding region of the MH1 domain by extracellular signal regulated kinase 1 (ERK1) enhances SMAD2 transcriptional activity, which is negatively regulated by calmodulin. In response to the TGF-beta signal, SMAD2 is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association wit |
|---|
| Immunogen | n/a |
|---|
| Other Names | JV18, JV18-1, MADH2, MADR2, SMAD family member 2, SMAD2, hMAD-2, hSMAD2 |
|---|
| Gene, Accession # | Entrez: 4087; Uniprot: Q15796 |
|---|
| Catalog # | PA5-78049 |
|---|
| Price | |
|---|
| Order / More Info | Phospho-SMAD2 (Ser245, Ser250, Ser255) Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|