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| Antigenic Specificity | CAD |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100µg |
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| Concentration | n/a |
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| Applications | ELISA, WB • WB 1:500 - 1:2000; IHC 1:50 - 1:100 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit anti-CAD polyclonal antibody. The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms. |
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| Immunogen | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase |
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| Other Names | n/a |
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| Gene, Accession # | Gene ID: 790, UniProt: P27708 |
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| Catalog # | FNab01183 |
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| Price | |
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| Order / More Info | CAD Antibody from FINETEST |
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| Product Specific References | n/a |
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