| 产品详情 |
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| Antigenic Specificity | SH2D1A |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100µg |
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| Concentration | n/a |
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| Applications | ELISA, WB • WB 1:500 - 1:2000; IHC 1:50 - 1:200 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit anti-SH2D1A polyclonal antibody. This gene encodes a protein that plays a major role in the bidirectional stimulation of T and B cells. This protein contains an SH2 domain and a short tail. It associates with the signaling lymphocyte-activation molecule, thereby acting as an inhibitor of this transmembrane protein by blocking the recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to its docking site. This protein can also bind to other related surface molecules that are expressed on activated T, B and NK cells, thereby modifying signal transduction pathways in these cells. Mutations in this gene cause lymphoproliferative syndrome X-linked type 1 or Duncan disease, a rare immunodeficiency characterized by extr |
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| Immunogen | SH2 domain protein 1A |
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| Other Names | DSHP, SAP |
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| Gene, Accession # | Gene ID: 4068, UniProt: O60880 |
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| Catalog # | FNab07819 |
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| Price | |
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| Order / More Info | SH2D1A Antibody from FINETEST |
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| Product Specific References | n/a |
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