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Product Name | Recombinant Human IL-36 Beta (IL-1F8) Protein |
Description | The IL-1 family is comprised of 11 structurally related ligands, including recently re-named IL-36α (IL-1F6), β (IL-1F8) and γ (IL-1F9). IL-36β is highly expressed in psoriatic plaques, and at lower levels in various other tissues. IL-36β signals through the IL-1Rrp2 (IL-1R6) receptor, which is primarily expressed on certain dendritic cells. The interaction of the IL-1Rrp2 receptor with IL-36 ligands induces dendritic cell maturation and activation. IL-36β also functions as an agonist of NF-kappaB, and stimulates the production of pro-inflammatory proteins, including IL-6, IL-8, BD-2, and BD-3. Recombinant human IL-36β is a 17.3 kDa protein containing 154 amino acid residues. |
Size | Various Sizes |
Concentration | n/a |
Applications | Cell Culture |
Other Names | Interleukin-36 beta;FIL1 eta;Interleukin-1 eta;IL-1 eta;Interleukin-1 family member 8;IL-1F8;Interleukin-1 homolog 2;IL-1H2;IL36B;IL1F8, IL1H2; IL-1F8 , IL-1H2, IL-1 eta |
Gene, Accession, CAS # | IL36B, UniProt: Q9NZH7-2 |
Catalog # | PROTQ9NZH7_2 |
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Order / More Info | Recombinant Human IL-36 Beta (IL-1F8) Protein from BOSTER BIO |
Product Specific References | n/a |
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