产品详情 |
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Antigenic Specificity | EGFR (pY1173) |
Clone | 10E3 |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | IgG |
Format | Protein A purified |
Size | 100ul |
Concentration | 1ug/ul |
Applications | IHC-P, IF(ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | EGFR (pY1173) (10E3) Monoclonal Antibody. • Target Background: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn a |
Immunogen | Synthetic peptide derived from human EGFR (pY1173), around 1150-1200aa (phospho Y1173). |
Other Names | Phosphorylated, phospho-ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1; EGFR |
Gene, Accession # | Gene ID: 1956, SwissProt: P00533 |
Catalog # | bsm-52147R |
Price | |
Order / More Info | EGFR (pY1173) Antibody from BIOSS ANTIBODIES |
Product Specific References | n/a |
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