| 产品详情 |
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| Product Name | Napabucasin |
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| Description | An inhibitor of cancer cell stemness; reduces growth in a panel of cancer cells enriched for high stemness (IC50s = 0.291-1.249 µM); decreases protein and gene expression of various self-renewal and pro-survival markers in FaDu HNSCC cells; inhibits tumor growth in a PaCa-2 mouse xenograft model and prevents tumor regrowth after cessation of treatment (20 mg/kg per day); blocks formation of spleen and liver metastases in an HT29 ISMS model; reduces tumor volume in PC3 and 22RV1 prostate cancer mouse xenograft models (40 mg/kg) |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | BBI 608 |
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| Gene, Accession, CAS # | CAS: 83280-65-3 |
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| Catalog # | 22255-10 |
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| Price | |
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| Order / More Info | Napabucasin from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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