| 产品详情 |
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| Antigenic Specificity | beta Catenin |
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| Clone | 15B8 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse |
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| Isotype | IgG1, kappa |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: Assay-Dependent, Immunohistochemistry (Paraffin): Assay-Dependent, Immunoprecipitation: Assay-Dependent, Western Blot: 1-5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | beta Catenin Monoclonal Antibody (15B8), eBioscience™. Beta-catenin, an adherens junction (AJ) protein, was originally identified as a component of cell-cell adhesion structures. AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. Beta-catenin interacts with the cytoplasmic domain of E-cadherin and links E-cadherin to alpha-catenin, which in turn mediates anchorage of the E-cadherin complex to the cortical actin cytoskeleton. Studies show that Beta-catenin also binds to another cytoskeletal complex containing the adenomatous polyposis coli protein and microtubules, and interacts with several signaling pathways that include tyrosine kinases, phosphatases and |
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| Immunogen | n/a |
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| Other Names | Cadherin associated protein, Catenin beta 1, CATNB, CTNNB |
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| Gene, Accession # | Entrez: 12387, 1499; Uniprot: P35222, Q02248 |
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| Catalog # | 14-2567-82 |
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| Price | |
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| Order / More Info | beta Catenin Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 23376424, 24184502, 26181204, 28901188 |
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