| 产品详情 |
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| Antigenic Specificity | beta Catenin |
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| Clone | 15B8 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, nonhuman primate, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Gel Shift: Assay Dependent, Immunocytochemistry: 1:50-1:1000, Immunofluorescence: 1:50 - 1:1000, Immunohistochemistry (Paraffin): 1:100 - 1:1000, Immunoprecipitation: Assay Dependent, Western Blot: 1:500 - 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | beta Catenin Monoclonal Antibody (15B8). Beta-catenin, an adherens junction (AJ) protein, was originally identified as a component of cell-cell adhesion structures. AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. Beta-catenin interacts with the cytoplasmic domain of E-cadherin and links E-cadherin to alpha-catenin, which in turn mediates anchorage of the E-cadherin complex to the cortical actin cytoskeleton. Studies show that Beta-catenin also binds to another cytoskeletal complex containing the adenomatous polyposis coli protein and microtubules, and interacts with several signaling pathways that include tyrosine kinases, phosphatases and Wnt/Wingless. The i |
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| Immunogen | n/a |
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| Other Names | Cadherin associated protein, Catenin beta 1, CATNB, CTNNB, beta-catenin, beta catenin, CTNNB1; |
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| Gene, Accession # | Entrez: 12387, 1499, 84353; Uniprot: P35222, Q02248, Q9WU82 |
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| Catalog # | MA1-301 |
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| Price | |
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| Order / More Info | beta Catenin Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 29213102, 29283884 |
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