| 产品详情 |
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| Antigenic Specificity | beta Catenin |
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| Clone | 15B8 |
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| Host Species | Mouse |
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| Reactive Species | avian, chicken, mammalia |
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| Isotype | IgG1 |
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| Format | Cyanine3 conjugate |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:100, Immunofluorescence: 1:100, Immunoprecipitation: Assay-Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | beta Catenin Monoclonal Antibody (15B8), Cyanine3. Beta-catenin, an adherens junction (AJ) protein, was originally identified as a component of cell-cell adhesion structures. AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. Beta-catenin interacts with the cytoplasmic domain of E-cadherin and links E-cadherin to alpha-catenin, which in turn mediates anchorage of the E-cadherin complex to the cortical actin cytoskeleton. Studies show that Beta-catenin also binds to another cytoskeletal complex containing the adenomatous polyposis coli protein and microtubules, and interacts with several signaling pathways that include tyrosine kinases, phosphatases and Wnt/Wingl |
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| Immunogen | n/a |
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| Other Names | CTNNB, DKFZp686D02253, FLJ25606, FLJ37923 |
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| Gene, Accession # | Entrez: 12387, 1499, 395964, 399274, 477032, 539003, 84353; Uniprot: B6V8E6, P26233, P35222, Q02248, Q0VCX4, Q9WU82 |
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| Catalog # | MA1-34999 |
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| Price | |
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| Order / More Info | beta Catenin Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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