| 产品详情 |
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| Antigenic Specificity | beta Catenin |
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| Clone | 9F2 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 10 µg/mL, Immunofluorescence: 10 µg/mL, Immunoprecipitation: 1 µg/mL, Western Blot: 1-3 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | beta Catenin Monoclonal Antibody (9F2). Beta-catenin, an adherens junction (AJ) protein, was originally identified as a component of cell-cell adhesion structures. AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. Beta-catenin interacts with the cytoplasmic domain of E-cadherin and links E-cadherin to alpha-catenin, which in turn mediates anchorage of the E-cadherin complex to the cortical actin cytoskeleton. Studies show that Beta-catenin also binds to another cytoskeletal complex containing the adenomatous polyposis coli protein and microtubules, and interacts with several signaling pathways that include tyrosine kinases, phosphatases and Wnt/Wingless. The in |
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| Immunogen | n/a |
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| Other Names | Cadherin associated protein, Catenin beta 1, CATNB, CTNNB |
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| Gene, Accession # | Entrez: 12387, 1499; Uniprot: P35222, Q02248 |
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| Catalog # | MA1-2001 |
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| Price | |
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| Order / More Info | beta Catenin Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 7650039, 7790378 |
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