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| Antigenic Specificity | C-Fos (aa 170-187), (Middle Region) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, rat |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | The human oncogene c-fos is cellular homolog of the transforming gene of Finkel-Biskis-Jinkins(FBJ) murine osteosarcoma virus which was mapped to a single human chromosome. c-Fos is encoded by the FOS gene. FOS was the first transcription factor identified that has a critical function in regulating the development of cells destined to form and maintain the skeleton. FOS is also a major component of the activator protein-1(AP-1) transcription factor complex, which includes members of the JUN family. c-fos is a major nuclear target for signal transduction pathways involved in the regulation of cell growth, differentiation, and transformation. Using transgenic and knockout mice, Grigoriadis et al.(1995) established a unique role for the proto-oncogene and nuclear transcription factor, Fos, in regulating the differentiation and activity of specific bone cell populations, both during normal development and in bone disease. |
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| Immunogen | A synthetic peptide corresponding to a sequence in the middle region of human c-Fos(170-187aa DQLEDEKSALQTEIANLL), identical to the related rat and mouse sequences. |
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| Other Names | AP-1|C-FOS|p55|c-fos|D12Rfj1|cFos|cFOS|fos |
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| Gene, Accession # | Gene ID: 2353,314322 |
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| Catalog # | ABIN1719806 |
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| Price | |
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| Order / More Info | C-Fos (aa 170-187), (Middle Region) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 22500715, 23054911, 21310774, 21080080, 20056141, 20979618, 18155486, 17828499, 17294041, 17499488, 17054583, 16866858, 15334674, 12632510, 12970873, 19575869, 22454845, 6091112, 7545543 |
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