| 产品详情 |
| Edit |   |
| Antigenic Specificity | CD57 |
| Clone | HCD57 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgM, κ |
| Format | allophycocyanin (APC) conjugate |
| Size | 25 tests |
| Concentration | n/a |
| Applications | Flow Cytometry (FC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | APC anti-human CD57. CD57, also known as HNK-1, NK-1, and Leu-7, is a 100-115 kD oligosaccharide antigenic determinant expressed on a variety of proteins, lipids, and chondroitin sulfate proteoglycans. CD57 is expressed on a subset of peripheral blood lymphocytes, including NK cells and CD8+ T cells, and is also expressed on neural cells and striated muscle. CD57 is not expressed on red cells, granulocytes, monocytes, or platelets. While the function of CD57 is unknown, binding to L-selectin, P-selectin, and a fragment of laminin suggests that CD57 may be involved in cell-matrix interactions. CD57 is increased in some disease states associated with CD4/CD8 imbalances (AIDS, autoimmune disease, viral infections, and allograft transplants). |
| Immunogen | n/a |
| Other Names | HNK-1, NK-1, Leu-7 |
| Gene, Accession # | Gene ID: 27087 |
| Catalog # | 322313 |
| Price | |
| Order / More Info | CD57 Antibody from BIOLEGEND |
| Product Specific References | PubMed: 21220772,21402893,23637420 |
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