| 产品详情 |
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| Antigenic Specificity | KMT1E/SETDB1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | Cy3 conjugate |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | IF(IHC-P) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | KMT1E/SETDB1 Polyclonal Antibody, Cy3 Conjugated. • Target Background: Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. H3 'Lys-9' trimethylation is coordinated with DNA methylation. Probably forms a complex with MBD1 and ATF7IP that represses transcription |
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| Immunogen | KLH conjugated synthetic peptide derived from human SETDB1. Immunogen Range: 210-260/1291 |
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| Other Names | ESET; KG1T; KMT1E; TDRD21; H3-K9-HMTase4; Histone-lysine N-methyltransferase SETDB1; ERG-associated protein with SET domain; Histone H3-K9 methyltransferase 4; H3-K9-HMTase 4; Lysine N-methyltransferase 1E; SET domain bifurcated 1; SETDB1; KIAA0067 |
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| Gene, Accession # | Gene ID: 9869, SwissProt: Q15047 |
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| Catalog # | bs-11670R-Cy3 |
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| Price | |
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| Order / More Info | KMT1E/SETDB1 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | n/a |
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