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| Antigenic Specificity | MAP3K8 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | Alexa Fluor® 647 conjugate |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | IF(IHC-P) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MAP3K8 Polyclonal Antibody, Alexa Fluor® 647 Conjugated. • Target Background: Required for lipopolysaccharide (LPS)-induced, TLR4-mediated activation of the MAPK/ERK pathway in macrophages, thus being critical for production of the proinflammatory cytokine TNF-alpha (TNF) during immune responses. Involved in the regulation of T-helper cell differentiation and IFNG expression in T-cells. Involved in mediating host resistance to bacterial infection through negative regulation of type I interferon (IFN) production. In vitro, activates MAPK/ERK pathway in response to IL1 in a |
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| Immunogen | KLH conjugated synthetic peptide derived from human MAP3K8. Immunogen Range: 140-190/467 |
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| Other Names | COT; EST; ESTF; TPL2; MEKK8; Tpl-2; c-COT; Mitogen-activated protein kinase kinase kinase 8; Cancer Osaka thyroid oncogene; Proto-oncogene c-Cot; Serine/threonine-protein kinase cot; Tumor progression locus 2; MAP3K8 |
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| Gene, Accession # | Gene ID: 1326, SwissProt: P41279 |
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| Catalog # | bs-3591R-A647 |
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| Price | |
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| Order / More Info | MAP3K8 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | n/a |
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