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| Antigenic Specificity | Caspase 4 |
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| Clone | polyclonal |
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| Host Species | Goat |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | peptide-ELISA: 1:16000, Western Blot: 0.3-1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Caspase 4 Polyclonal Antibody. This gene encodes a protein that is a member of the cysteine-aspartic acid protease family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. |
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| Immunogen | n/a |
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| Other Names | CASP4; TX; ICH-2; Mih1/TX; ICEREL-II; ICE(rel)II; caspase 4, apoptosis-related cysteine protease; apoptotic cysteine protease Mih1/TX; caspase 4 |
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| Gene, Accession # | Entrez: 837; Uniprot: P49662 |
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| Catalog # | PA5-18300 |
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| Price | |
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| Order / More Info | Caspase 4 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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