| 产品详情 |
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| Antigenic Specificity | Caspase 4 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Caspase 4 Polyclonal Antibody. This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. |
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| Immunogen | n/a |
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| Other Names | ICE(rel)II, ICEREL-II, ICH-2, Mih1/TX, TX, CASP-4, ICE(rel)-II, apoptotic cysteine protease Mih1/TX, caspase 4, apoptosis-related cysteine protease, caspase-4, protease ICH-2, protease TX |
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| Gene, Accession # | Entrez: 837; Uniprot: P49662 |
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| Catalog # | PA5-29788 |
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| Price | |
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| Order / More Info | Caspase 4 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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