| 产品详情 |
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| Antigenic Specificity | Caspase 6 |
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| Clone | 6CSP03 (14.1.190) |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1, kappa |
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| Format | purified |
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| Size | 500 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 2 µg/mL, Immunofluorescence: 2 µg/mL, Immunoprecipitation: 2 µg/mL, Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Caspase 6 Monoclonal Antibody (6CSP03 (14.1.190)). Caspases play a major role in the transduction of the apoptotic signal and execution of apoptosis in mammalian cells. Caspase 3 (CPP32) and Caspase 6 (Mch2) are the major active caspases in apoptotic cells, and are activated in response to distinct apoptosis-inducing stimuli and in all cell lines analyzed. Both CPP32 and Mch2 are present in apoptotic cells as multiple active species. Caspase-6 cleaves nuclear mitotic apparatus protein (NuMA) and mediates the shrinkage and fragmentation of nuclei. |
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| Immunogen | n/a |
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| Other Names | CASP-6, apoptotic protease MCH-2, caspase 6, apoptosis-related cysteine protease, caspase-6 |
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| Gene, Accession # | Entrez: 839; Uniprot: P55212 |
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| Catalog # | MA5-11527 |
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| Price | |
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| Order / More Info | Caspase 6 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 16977583, 19133298, 20682790, 26412386 |
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