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| Product Name | TPM3-ROS1 Mutant, Active |
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| Description | 1-258 (TPM3) - 1881-end (ROS1). MW: 108 kDa. Description: Recombinant human fusion protein TPM3 (1-258)-ROS1 (1881-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: TPM3 is a member of the tropomyosin family of actin-binding proteins which are dimers of coiled-coil proteins that provide stability to actin filaments and regulate access of other actin-binding proteins. Mutations in TPM3 gene result in autosomal dominant nemaline myopathy a |
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| Size | 0.005 mg, 0.01 mg |
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| Concentration | n/a |
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| Applications | Kinase Assay |
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| Other Names | [Homo sapiens tropomyosin 3 (TPM3), transcript variant Tpm3.12, mRNA; Tropomyosin alpha-3 chain; tropomyosin alpha-3 chain; tropomyosin 3; Gamma-tropomyosin; Tropomyosin-3; Tropomyosin-5; hTM5] |
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| Gene, Accession, CAS # | TPM3-ROS1, Gene ID: 7170, Accession: NM_152263.3 |
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| Catalog # | MBS515651 |
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| Order / More Info | TPM3-ROS1 Mutant, Active from MYBIOSOURCE INC. |
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| Product Specific References | 1. Lawlor, M W. et al: Mutations of tropomyosin 3 (TPM3) are common and associated with type 1 myofiber hypotrophy in ongenital fiber type disproportion. Hum Mutat. 2010 Feb;31 (2):176-83. 2. Zhao C. et al: Detecting ALK, ROS1 and RET Fusion Genes in Cell Block Samples. Transl Oncol. 2014 Jun 17;7 (3):363-7. |
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