| 产品详情 |
| Edit |   |
|---|
| Product Name | TPMT, 1-245aa, Human, E.coli |
|---|
| Description | Purity: > 95% by SDS - PAGE Format: In 20mM Tris 8.0, 0.2mM PMSF, 2mM EDTA . TPMT, thiopurine S-methyltransferase, is a cytosolic enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine and azathioprine are used as chemotherapeutic agents. TPMT activity exhibits autosomal codominant genetic polymorphism, and patients inheriting TPMT-deficiency are at high risk of potentially fatal hematopoietic toxicity. Recombinant human TPMT was expressed in E.coli and purified by using conventional chromatography techniques. |
|---|
| Size | 0.5mg, 100ug, 20ug |
|---|
| Concentration | n/a |
|---|
| Applications | SDS-PAGE |
|---|
| Other Names | Thiopurine S-methyltransferase, Thiopurine S-methyltransferase, TPMT, Thiopurine S-methyltransferase HGNC:12014, S adenosyl L methionine thiopurine S methyltransferase, Thiopurine methyltransferase, Thiopurine S methyltransferase. |
|---|
| Gene, Accession, CAS # | AAH05339 |
|---|
| Catalog # | TPM0701 |
|---|
| Price | |
|---|
| Order / More Info | TPMT, 1-245aa, Human, E.coli from ATGen |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|