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| Product Name | TPM3-TRKA Mutant, Active |
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| Description | 1-258 (TPM3) - 399-end (TRKA). MW: ~105 kDa. Description: Recombinant human fusion protein TPM3 (1-258)-TRKA (399-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family which is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. TRKA has a crucial role in the development and function of the nociceptive rec |
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| Size | 0.005 mg, 0.01 mg |
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| Concentration | n/a |
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| Applications | Kinase Assay |
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| Other Names | [Homo sapiens tropomyosin 3 (TPM3), transcript variant Tpm3.12, mRNA; Tropomyosin alpha-3 chain; tropomyosin alpha-3 chain; tropomyosin 3; Gamma-tropomyosin; Tropomyosin-3; Tropomyosin-5; hTM5] |
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| Gene, Accession, CAS # | TPM3-TRKA, Gene ID: 7170, Accession: NM_152263.3 |
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| Catalog # | MBS515560 |
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| Order / More Info | TPM3-TRKA Mutant, Active from MYBIOSOURCE INC. |
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| Product Specific References | 1. Smeyne, R. J. et.al: Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGF receptor gene. Nature 368: 246-249, 1994. 2. Marta G. B. et.al: A Sequence Analysis of the Genomic Regions Involved in the Rearrangements between TPM3 and NTRK1 Genes Producing TRK Oncogenes in Papillary Thyroid Carcinomas. Genomics, Volume 28, Issue 1, 1 July 1995, Pages 15 -24 |
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