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| Product Name | Nanog |
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| Description | Highly Purified. C-QNQRMKSKRWQKNN, from the internal region of human NANOG. Control peptide corresponding to polyclonal antibody, Catalog#N0019-01K, goat x human. NANOG is a unique variant of NK2 family of transcription factors. It is a human ortholog of mouse Nanog and consists of a highly conserved homeodomain and Trp-rich repeats. It is specifically expressed by embryonic stem cells and is crucial for second embryonic lineage determination. It works in concert with OCT-4 and SOX-2 and plays a central role in regulating pluripotency and self-renewal of ICM and ES cells. It functions independent of LIF/gp130/Stat3 pathway and prevents differentiation of ES cells to extraembryonic endoderm and trophectoderm lineages. Its expression has also been detected in embryonic carcinoma cells and germ line tumors indicating a therapeutic intervention Applications: Suitable for use in ELISA. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | Nanog (Early Embryo Specific Expression NK Family Gene, Embryonic Stem Cell Specific Homeobox Protein, ENK, FLJ12581, FLJ40451, Homeobox Transcription Factor Nanog, Nanog Homeobox) (Control Peptide) |
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| Gene, Accession, CAS # | Accession: NP_079141.1 |
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| Catalog # | N0019-01K-P |
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| Order / More Info | Nanog from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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