| 产品详情 |
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| Product Name | 17-AAG |
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| Description | Inhibitor of heat shock protein 90 (Hsp90) chaperone activity, and an analog of geldanamycin (Cat. No. 1368). Subsequently inhibits the activity of oncogenic proteins such as p185erbB-2 (IC50 = 31 nM), N-ras, Ki-ras and c-Akt. Antitumor in vivo. Also protects neuroprogenitor cells against stress-induced apoptosis at low concentrations (10 nM) in vitro. Purity 98%. MW (observed): 585.7 |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 17-Demethoxy-17-(2-propenylamino)geldanamycin. NSC 330507, 17-(Allylamino)-17-demethoxygeldanamycin, Tanespimycin |
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| Gene, Accession, CAS # | Gene ID: 3320, CAS: 75747-14-7 |
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| Catalog # | 1515/1 |
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| Price | |
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| Order / More Info | 17-AAG from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 24281706, 25205676, 25423885, 25452130 |
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