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| Product Name | Recombinant Human Ganglioside GM2 activator protein |
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| Description | 32-193aa; Full Length. MW: 45kD. Purity >90% as determined by SDS-PAGE. The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity. Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from membranes and presents th in soluble form to beta-hexosaminidase A fo |
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| Size | 0.01 mg, 0.05 mg, 0.1 mg, 0.2 mg, 0.5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Cerebroside sulfate activator protein; GM2-AP; Sphingolipid activator protein 3; SAP-3] |
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| Gene, Accession, CAS # | GM2A, Gene ID: 2760, Accession: NP_000396.2 |
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| Catalog # | MBS717112 |
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| Order / More Info | Recombinant Human Ganglioside GM2 activator protein from MYBIOSOURCE INC. |
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| Product Specific References | Isolation and expression of a full-length cDNA encoding the human G-M2 activator protein.Xie B., McInnes B., Neote K., Lamhonwah A.-M., Mahuran D.Biochem. Biophys. Res. Commun. 177:1217-1223(1991) Characterization of full-length cDNAs and the gene coding for the human GM2 activator protein.Klima H., Tanaka A., Schnabel D., Nakano T., Schroeder M., Suzuki K., Sandhoff K.FEBS Lett. 289:260-264(1991) Evidence for two cDNAs encoding human GM2-activator protein.Nagarajan S., Chen H.C., Li S.C., Li Y. |
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