| 产品详情 |
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| Product Name | SP-600125 |
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| Description | MW: 110.2. Purity ≥98% (TLC; 1:1 ethylacetate: hexane; Rf=0.17); NMR (conforms). JNK inhibitorA highly selective inhibitor of Chk2 (IC50=15 nM). Displays <25% inhibition of 35 other kinases at 10 mM)1. It possesses potent radioprotective activity and prevents apoptosis of human T-cells subjected to ionizing radiation (EC50= 3-7.6 mM)1. It is a useful tool for determining the role of Chk2 in cellular signaling2.Scientific Background: Selective inhibitor of c-Jun N-terminal k |
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| Size | 5 mg, 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [BML-277 ; 2-(4-(4-chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide; Chk2 Inhibitor II; Anthra [1-9-cd] pyrazol-6(2H)-one; 1,9-Pyrazoloanthrone] |
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| Gene, Accession, CAS # | CAS: 129-56-6 |
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| Catalog # | MBS515045 |
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| Order / More Info | SP-600125 from MYBIOSOURCE INC. |
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| Product Specific References | 1. K L Arienti et al. J. Med. Chem. 2005 48:1873 2. Y Pereg et al. Mol. Cell. Biol. 2006 26:6819 |
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