产品详情 |
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Product Name | PRT060318 |
Description | A potent and selective Syk inhibitor (IC50 = 4 nM); inhibits 92% of Syk activity, while other kinases retain >70% activity, at a concentration of 50 nM in a panel of 270 kinases; inhibits convulxin-induced aggregation of human platelet-rich plasma (IC50 = 2.5 µM); prevents thrombosis in a transgenic mouse model of heparin-induced thrombocytopenia; induces CLL B cell apoptosis and inhibits the secretion of chemokines CCL3, CCL4, and CXCL13; inhibits CLL B cell chemotaxis and pseudoemperipolesis, |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | P142-76|PRT318 |
Gene, Accession, CAS # | CAS: 1194961-19-7 |
Catalog # | 22476-5 |
Price | |
Order / More Info | PRT060318 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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