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Product Name | Mivacurium (chloride) |
Description | An antagonist of nAChRs and muscarinic M2 and M3 receptors (ED50s = 0.08, 0.3, and 0.1 mg/kg for ex vivo human skeletal muscle nAChRs, guinea pig cardiac M2 receptors, and guinea pig bronchial M3 receptors, respectively); inhibits acetylcholine-induced activation of neuronal nAChRs (IC50s = 69.04, 3.71, 1.52, and 2.90 for human α3β2-, α3β4-, α4β2-, and α7-containing nAChRs expressed in Xenopus oocytes); inhibits adult human muscular α1β1εδ-containing nAChRs (IC50 = 3.69 nM in Xenopus oocytes expressing the human recombinant receptor); inhibits bradycardia and bronchoconstriction induced by vagal stimulation or acetylcholine in guinea pigs; induces neuromuscular blockade in sheep (ED95 = 80 µg/kg) |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 133814-19-4 BW-B 1090U BW-B1090U BWB1090U Mivacron Nicotinic acetylcholine |
Gene, Accession, CAS # | CAS: 106861-44-3 |
Catalog # | 23610-5 |
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Order / More Info | Mivacurium (chloride) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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