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| Product Name | Recombinant Human TRAF family member-associated NF-kappa-B activator |
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| Description | 1-119aa; Partial. MW: 41kD. Purity >90% as determined by SDS-PAGE. Adapter protein involved in I-kappa-B-kinase (IKK) regulation which constitutively binds TBK1 and IKBKE playing a role in antiviral innate immunity. Acts as a regulator of TRAF function by maintaining th in a latent state. Blocks TRAF2 binding to LMP1 and inhibits LMP1-mediated NF-kappa-B activation. May control negatively TRAF2-mediated NF-kappa-B activation signaled by CD40, TNFR1 and TNFR2. |
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| Size | 0.01 mg (E-Coli), 0.01 mg (Yeast), 0.05 mg (E-Coli), 0.05 mg (Yeast), 0.1 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [TRAF-interacting protein; I-TRAF] |
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| Gene, Accession, CAS # | TANK, Gene ID: 10010, Accession: NP_001186064.1 |
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| Catalog # | MBS1265413 |
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| Order / More Info | Recombinant Human TRAF family member-associated NF-kappa-B activator from MYBIOSOURCE INC. |
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| Product Specific References | I-TRAF is a novel TRAF-interacting protein that regulates TRAF-mediated signal transduction.Rothe M., Xiong J., Shu H.-B., Williamson K., Goddard A., Goeddel D.V.Proc. Natl. Acad. Sci. U.S.A. 93:8241-8246(1996) |
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