| 产品详情 |
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| Antigenic Specificity | USP34 Core |
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| Clone | polyclonal |
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| Host Species | Chicken |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | Western blot |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Polyclonal antibody to detect USP34 Core (a DUB enzyme) in human samples. USP34 Core is a ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. It acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin (CTNBB1)-mediated transcription. It recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. It is involved in the processing of poly-ubiquitin precursors as well as that of ubiquinated proteins. Its catalytic core consists of residues 1892-2241. |
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| Immunogen | Recombinant full length protein |
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| Other Names | FLJ43910, KIAA0570, KIAA0729, Ubiquitin Specific Protease 34 core domain. |
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| Gene, Accession # | Gene ID: 9736, Accession: Q70CQ2 |
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| Catalog # | 6136-50 |
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| Price | |
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| Order / More Info | USP34 Core Antibody from BIOVISION, INC. |
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| Product Specific References | n/a |
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