| 产品详情 |
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| Antigenic Specificity | CD38 |
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| Clone | 6E12D |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | ascites |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | ELISA,Western Blotting (WB),Immunohistochemistry (IHC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD38 is a type II integral membrane glycoprotein which is present on early B and T cell lineages and activated B and T cells but is absent from most mature resting peripheral lymphocytes. CD38 is also found on thymocytes, pre-B cells, germinal center B cells, mitogen-activated T cells, monocytes and Ig-secreting plasma cells. CD38 acts as a NAD glycohydrolase in T lym- phocytes. On hematopoietic cells CD38 induces activation, proliferation, and differentiation of mature T and B cells and mediates apoptosis of myeloid and lymphoid progenitor cells. In addition to acting as a signaling receptor, CD38 is also an enzyme capable of producing several calcium-mobilizing metabo- lites, including cyclic adenosine diphosphate ribose (cADPR). CD38 also plays a role in maintaining survival of an invariant NK T (iNKT) cell subset that preferentially contributes to the maintenance of immunological tolerance. |
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| Immunogen | Purified recombinant fragment of human CD38 expressed in E. coli. |
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| Other Names | Cd38-rs1|T10 |
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| Gene, Accession # | Gene ID: 952 |
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| Catalog # | ABIN969023 |
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| Price | |
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| Order / More Info | CD38 Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 15964076, 12063025 |
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