| 产品详情 |
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| Antigenic Specificity | Cytokeratin 16 |
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| Clone | LL025 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 500 µL |
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| Concentration | n/a |
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| Applications | Immunofluorescence: Assay Dependent, Immunohistochemistry (Paraffin): 1-2 µg/mL, Western Blot: 2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Cytokeratin 16 Monoclonal Antibody (LL025). Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 16 is absent in normal breast tissue and in noninvasive breast carcinomas. Only 10% of the invasive breast carcinomas show diffuse or focal positivity. Reportedly, a relatively high concordance was found between the carcinomas immunostaining with the basal cell and the hyperproliferation-related keratins, but not between these markers and the proliferation marker Ki-67. This supports the conclusion that basal cells in breast cancer may show extensive proliferation, and that absence of Ki-67 staining does not mean that (tumor) ce |
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| Immunogen | n/a |
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| Other Names | CK-16, cytokeratin 16, cytokeratin-16, focal non-epidermolytic palmoplantar keratoderma, keratin, type I cytoskeletal 16, keratin-16 |
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| Gene, Accession # | Entrez: 3868; Uniprot: P08779 |
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| Catalog # | MA5-13730 |
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| Price | |
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| Order / More Info | Cytokeratin 16 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 12366694, 15141317, 15342384, 16176455, 18413645, 18557933, 18829709, 18985776, 19040521, 21150925, 21371075, 22169155, 25850823, 26738450, 28232470 |
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