| 产品详情 |
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| Antigenic Specificity | N4BP1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 10 µg/mL, Immunofluorescence: 20 µg/mL, Western Blot: 0.5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | N4BP1 Polyclonal Antibody. Nedd4-binding partner-1 (N4BP1) is a developmentally expressed protein interactor and monoubiquitylation substrate of Nedd4, a HECT domain-containing ubiquitin ligase that mediates ubiquitylation and proteasome degradation of target proteins and may have a fundamental role to play in embryonic processes. N4BP1 can undergo Nedd4-mediated polyubiquitylation and proteosomal degradation. N4BP1 also functions as a negative regulator of AIF4 (also known as ITCH or Atrophin-1), an E3-ubiquitin ligase, by interacting with the second WW domain of AIF4 and impairing ubiquitination of substrates. |
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| Immunogen | n/a |
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| Other Names | NEDD4-binding protein 1 |
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| Gene, Accession # | Entrez: 291921, 80750, 9683; Uniprot: O75113, Q6A037 |
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| Catalog # | PA5-21099 |
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| Price | |
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| Order / More Info | N4BP1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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