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Product Name | Recombinant Mycobacterium tuberculosis Toxin RelG (relG) |
Description | Purity > 90% as determined by SDS-PAGE. MW: 26.2kDa. Full Length: 1-87aa. N-terminal 6xHis-SUMO-tagged. Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv). Toxic component of a toxin-antitoxin (TA) module. Has RNase activity and preferentially cleaves at the 3'-end of purine ribonucleotides. Overexpression in M.tuberculosis or M.smegmatis inhibits colony formation in a bacteriostatic rather than bacteriocidal fashion. Its toxic effect is neutralized by coexpression with cognate antitoxin RelB2 (shown only for M.smegmatis). Overexpression also increases the number of gentamicin-tolerant and levofloxacin-tolerant persister cells. |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | Putative endoribonuclease RelG |
Gene, Accession, CAS # | relG, UniProt: O33348 |
Catalog # | RPC22893 |
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Order / More Info | Recombinant Mycobacterium tuberculosis Toxin RelG (relG) from BIOMATIK |
Product Specific References | n/a |
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