| 产品详情 |
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| Product Name | Tunicamycin |
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| Description | A specific inhibitor of N-linked glycoslylation that blocks the first step of glycoprotein synthesis and induces protein unfolding; impairs the function of several receptor tyrosine kinases, including EGFR, ErbB2, ErbB3, IGF-IR, and ALK; radiosensitizes glioma and pancreatic adenocarcinoma cells to chemotherapy (500 nM) and disrupts cell viability in various neuroblastoma cell lines (IC50s 20 - 500 nM) |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 11118-26-6 N-linked glycosylation post-translational modifications proteins folding inhibitors inhibition inhibits antibiotics glycoproteins EGFR ErbB2 ErbB3 IGF-IR ALK cancers palmitoylation oligomerization cells endoplastic reticulum amino acids Golgi plasma membranes nucleoside U251 glioma BXPC3 phosphorylation |
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| Gene, Accession, CAS # | CAS: 11089-65-9 |
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| Catalog # | 11445-1 |
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| Price | |
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| Order / More Info | Tunicamycin from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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