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| Product Name | Recombinant Human Myeloid differentiation primary response protein MyD88 (MYD88) |
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| Description | Purity > 85% as determined by SDS-PAGE. MW: 37.2kDa. Full Length: 1-296aa. N-terminal 6xHis-tagged. Homo sapiens (Human). Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes. MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | n/a |
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| Gene, Accession, CAS # | MYD88, UniProt: Q99836 |
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| Catalog # | RPC26047 |
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| Price | |
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| Order / More Info | Recombinant Human Myeloid differentiation primary response protein MyD88 (MYD88) from BIOMATIK |
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| Product Specific References | n/a |
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