| 产品详情 |
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| Product Name | NSC 405020 |
| Description | MW: 260.16. Purity ≥98% by HPLC. Background: NSC-405020 is a membrane type-I matrix metalloproteinase (MT1-MMP) inhibitor that specifically targets the hemopexin (PEX) domain rather than the catalytic domain of MT1-MMP (IC?? >100 mumol/L). It does not inhibit the catalytic activity of MT1-MMP or MMP-2. NSC-405020 directly interacts with and binds to PEX in a vicinity of Met-328, Arg-330, Asp-376, Met-22 and Ser-470 of the druggable pocket in the full-length MT1-MMP structure, which affects th |
| Size | 5 mg, 25 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | [3,4-Dichloro-N-(1-methylbutyl)benzamide] |
| Gene, Accession, CAS # | [NSC 405020] |
| Catalog # | MBS843273 |
| Price | |
| Order / More Info | NSC 405020 from MYBIOSOURCE INC. |
| Product Specific References | n/a |
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