| 产品详情 |
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| Product Name | NSC-59984 |
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| Description | MW: 265.27. Purity ≥98% by HPLC. NSC-59984 is a p53 pathway activator that induces mutant p53 protein degradation via MDM2 and the ubiquitin-proteasome pathway. The EC50 of NSC-59984 in most cancer cells is significantly lower than those of normal cells; with EC50 of 8.38 muM for p53-null HCT116 cells. NSC-59984 induces p73-dependent cell apoptosis in cancer in vivo. |
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| Size | 5 mg, 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [(E)-1- (4-methylpiperazin-1-yl)-3- (5-nitrofuran-2-yl) prop-2-en-1-one] |
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| Gene, Accession, CAS # | CAS: 803647-40-7 |
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| Catalog # | MBS846199 |
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| Price | |
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| Order / More Info | NSC-59984 from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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