| 产品详情 |
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| Antigenic Specificity | MLH1 |
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| Clone | CBFYM-2294 |
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| Host Species | Recombinant Rabbit |
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| Reactive Species | human, monkey |
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| Isotype | IgG |
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| Format | unconjugated |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | IP, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit Anti-MLH1 Recombinant Antibody (CBFYM-2294). This product is rabbit antibody that recognizes MLH1. The antibody CBFYM-2294 can be used for immunoassay techniques such as: IP, WB. The protein encoded by this gene can heterodimerize with mismatch repair endonuclease PMS2 to form MutL alpha, part of the DNA mismatch repair system. When MutL alpha is bound by MutS beta and some accessory proteins, the PMS2 subunit of MutL alpha introduces a single-strand break near DNA mismatches, providing an entry point for exonuclease degradation. The encoded protein is also involved in DNA damage signaling and can heterodimerize with DNA mismatch repair protein MLH3 to form MutL gamma, which is involved in meiosis. This gene was identified as a locus |
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| Immunogen | Synthetic peptide corresponding to residues near the amino terminus of human MLH1 protein (KLH coupled) |
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| Other Names | MutL Homolog 1; COCA2; MutL (E. Coli) Homolog 1 (Colon Cancer, Nonpolyposis Type 2); MutL Homolog 1, Colon Cancer, Nonpolyposis Type 2 (E. Coli); MutL Homolog 1, Colon Cancer, Nonpolyposis Type 2; DNA Mismatch Repair Protein Mlh1 |
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| Gene, Accession # | Gene ID: 4292, UniProt: P40692 |
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| Catalog # | CBMAB-M2479-FY |
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| Price | |
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| Order / More Info | MLH1 Antibody from CREATIVE BIOLABS |
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| Product Specific References | n/a |
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