| 产品详情 |
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| Antigenic Specificity | UHRF1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100µg |
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| Concentration | n/a |
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| Applications | ELISA, WB, IF • WB 1:500 - 1:2000; IHC 1:50 - 1:200; IF 1:20 - 1:50 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit anti-UHRF1 polyclonal antibody. This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. It is regarded as a hub protein for the integration of epigenetic information. This gene is up-regulated in various cancers, and it is therefore considered to be a therapeutic target. Multiple transcript variants encoding different isoforms have bee |
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| Immunogen | ubiquitin-like with PHD and ring finger domains 1 |
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| Other Names | FLJ21925, hNP95, HuNp95, ICBP90, Nuclear protein 95, RING finger protein 106, RNF106, Transcription factor ICBP90, UHRF1 |
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| Gene, Accession # | Gene ID: 29128, UniProt: Q96T88 |
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| Catalog # | FNab09245 |
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| Price | |
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| Order / More Info | UHRF1 Antibody from FINETEST |
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| Product Specific References | n/a |
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| 产品资料 |
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