| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | FBW7 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | affinity purified |
|---|
| Size | 100 ul |
|---|
| Concentration | n/a |
|---|
| Applications | WB |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Rabbit polyclonal to FBW7.F-box/WD repeat-containing protein 7 (FBXW7) is a substrate recognition component of a SCF(SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination andsubsequent proteasomal degradation of target proteins. FBXW7 probably recognizes and binds tophosphorylated target proteins. FBXW7 is involved in the degradation of cyclin-E, MYC, NOTCH1released notch intracellular domain (NICD), and probably PSEN1. |
|---|
| Immunogen | N-terminal region of human DDB1 |
|---|
| Other Names | FBW7,Fbox,WD repeatcontaining protein 7,Archipelago homolog,hAgo,Fbox and WD40 domaincontainingprotein 7,Fbox protein FBX30,SEL10,hCdc4,FBW7,FBX30,SEL10 |
|---|
| Gene, Accession # | UniProt: Q969H0 |
|---|
| Catalog # | orb67185 |
|---|
| Price | |
|---|
| Order / More Info | FBW7 Antibody from BIORBYT LTD. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|