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| Product Name | PKLR, 47-574aa, Human, His tag, E.coli (Bioactivity Validated) |
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| Description | Purity: > 90% by SDS - PAGE Format: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 1mM DTT, 10% glycerol . PKLR is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. The PKLR gene encodes the L- and R-type isoenzymes through alternative splicing events under the control of different promoters. The L-type isoform also exists as a tetramer and is upregulated by glucose with implications in maturity-onset diabetes of the young. Recombinant human PKLR protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
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| Size | 250ug, 50ug, 10ug |
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| Concentration | n/a |
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| Applications | Enzyme activity |
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| Other Names | Pyruvate kinase isozymes R/L, PK1, PKL, PKR, PKRL, RPK |
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| Gene, Accession, CAS # | NP 000289 |
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| Catalog # | ATGP0714 |
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| Order / More Info | PKLR, 47-574aa, Human, His tag, E.coli (Bioactivity Validated) from ATGen |
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| Product Specific References | n/a |
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