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| Product Name | PKM2, 1-531aa, Human, His tag, E Coli (Bioactivity Validated) |
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| Description | MW: 60.1 kDa (551aa). Purity >95% by SDS-PAGE. PKM2 is an isoenzyme of the glycolytic enzyme pyruvate kinase. This protein catalyzes the production of pyruvate and ATP from phosphoenolpyruvate. PKM2 interacting with Opa proteins, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, is required for bacterial pathogenesis. It is specifically expressed at high levels in tumor cells, and can be measured in plasma of patients with advanced breast cancer. |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [pyruvate kinase muscle isoform M2; CTHBP; THBP1; p58; M2-PK; Tumor M2-PK; PK2; PK3; PKM; pyruvate kinase; muscle isoform M2 OIP3; PKM; TCB; OPA interacting protein 3; PKM2; Cytosolic thyroid hormone binding protein; Pyruvate kinase 2/3; Pyruvate kinase isozymes M1/M2; Pyruvate kinase muscle; Thyroid hormone binding protein cytosolic; Tumour Type M2 Pyruvate Kinase; Tumor Type M2 Pyruvate Kinase] |
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| Gene, Accession, CAS # | PKM2, Gene ID: 5315, Accession: NP_002645 |
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| Catalog # | MBS203644 |
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| Order / More Info | PKM2, 1-531aa, Human, His tag, E Coli (Bioactivity Validated) from MYBIOSOURCE INC. |
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| Product Specific References | Zwerschke W., et al. (2009). Exp Cell Res. 315 (16):2765-74; Mazurek S., et al. (2007). Ernst Schering Found Symp Proc. (4):99-124.; |
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