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| Product Name | Recombinant Human Tumor susceptibility gene 101 protein (TSG101), partial |
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| Description | 1-145aa. MW: 36.6 kDa. Purity >85% as determined by SDS-PAGE. Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regula |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [ESCRT-I complex subunit TSG101] |
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| Gene, Accession, CAS # | TSG101, Gene ID: 7251, Accession: NP_006283.1 |
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| Catalog # | MBS7110964 |
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| Order / More Info | Recombinant Human Tumor susceptibility gene 101 protein (TSG101), partial from MYBIOSOURCE INC. |
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| Product Specific References | The TSG101 tumor susceptibility gene is located in chromosome 11 band p15 and is mutated in human breast cancer. Li L., Li X., Francke U., Cohen S.N.Cell 88:143-154 (1997) |
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