| 产品详情 |
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| Product Name | ABT-869 |
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| Description | Purity >99%. ABT-869 is multi-targeted inhibitor of all members of the VEGF and PDGF receptor families (e.g., KDR, IC50 value of 4 nM), but has much less activity (IC50 values >1 µM) against unrelated receptor tyrosine kinases, soluble tyrosine kinases or serine/threonine kinases. The kinase inhibition profile of ABT-869 is evident in cellular assays of RTK phosphorylation (IC50 values of 2, 4 and 7 nM for PDGFRBeta, KDR and CSF-1R, respectively) and VEGF-stimulated proliferation (0.2 nM IC50 for human endothelial cells). |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Linifanib |
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| Gene, Accession, CAS # | CAS: 796967-16-3 |
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| Catalog # | LS-H2342 |
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| Price | |
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| Order / More Info | ABT-869 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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